Downtown Syracuse Vacations from $305

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Your Downtown Syracuse Vacation

A sought-after riverside neighborhood, Downtown Syracuse tempts travelers with its bars and pubs, nightlife and shopping. Lock in a vacation package to Downtown Syracuse and experience all the highlights for yourself. Some nearby attractions to visit during your trip to Downtown Syracuse include Museum of Science and Technology, Erie Canal Museum and Syracuse University. Stop dreaming and start doing. When you're ready to lock in your next vacation to Downtown Syracuse, Expedia will help you get there.

The Latest Downtown Syracuse Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Syracuse Grand
The Craftsman Inn & Suites
Cicero Grand - Syracuse North
DoubleTree by Hilton Hotel Syracuse
Holiday Inn Express Syracuse Fairgrounds by IHG

Where to stay in Downtown Syracuse

Find the best Downtown Syracuse areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Syracuse

Downtown Syracuse Hotel Deals

Marriott Syracuse Downtown

Marriott Syracuse Downtown

4 out of 5
100 East Onondaga Street Syracuse NY
Fully refundableReserve now, pay when you stay
$159 nightly
The price is $186 total per night from Nov 15 to Nov 16
$186 total
Nov 15 - Nov 16
Total with taxes and fees
Marriott Syracuse Downtown
Best Western Syracuse Downtown Hotel and Suites

Best Western Syracuse Downtown Hotel and Suites

3 out of 5
416 S Clinton St Syracuse NY
Fully refundableReserve now, pay when you stay
$120 nightly
The price is $140 total per night from Nov 15 to Nov 16
$140 total
Nov 15 - Nov 16
Total with taxes and fees
8.4/10 Very Good! (775 reviews)
"Well situated in Armory Square and the staff is terrific. Very friendly and helpful. The area has museums, restaurants, coffee shops, etc all within walking was distance. Breakfast buffet was decent"

Reviewed on Nov 1, 2026

Best Western Syracuse Downtown Hotel and Suites
Courtyard by Marriott Syracuse Downtown at Armory Square

Courtyard by Marriott Syracuse Downtown at Armory Square

3 out of 5
300 West Fayette Street Syracuse NY
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $168 total per night from Nov 22 to Nov 23
$168 total
Nov 22 - Nov 23
Total with taxes and fees
8.6/10 Excellent! (774 reviews)
"nice and clean"

Reviewed on Oct 29, 2026

Courtyard by Marriott Syracuse Downtown at Armory Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Downtown Syracuse attractions

Things to do

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.